Osteomalacia
Overview
What is osteomalacia?
Osteomalacia means "soft bones." Osteomalacia is a disease that weakens bones and can cause them to break more easily. It is a disorder of decreased mineralization, which results in bone breaking down faster than it can re-form. It is a condition that occurs in adults. In children, inadequate concentrations of vitamin D may cause rickets.
Symptoms and Causes
What causes osteomalacia?
Osteomalacia develops most commonly due to avitamin D deficiency从没有得到足够的阳光(通常),或更少frequently, due to a digestive or kidney disorder. Vitamin D is essential for calcium absorption and for maintaining bone health. These disorders can interfere with the body's ability to absorb vitamins. There are also rare genetic conditions that can cause osteomalacia.
What are the symptoms of osteomalacia?
The most common symptoms of osteomalacia are pain in the bones and hips,bone fractures, and muscle weakness. Patients can also have difficulty walking.
Diagnosis and Tests
How is osteomalacia diagnosed?
There are various tests that can be performed to determine if someone has osteomalacia.
- The most important indicator islow levels of vitamin D, but low levels of calcium or a significant drop in phosphate levels may also indicate osteomalacia.
- X-rays may be taken to see if there is any evidence of osteomalacia.
- A bone mineral density scan may be helpful in evaluating the amount of calcium and other minerals present in a patient’s bone segment. These scans are not required to make the diagnosis of osteomalacia. However, they may give important information about a patient’s bone health.
Rarely, the doctor may perform a bone biopsy, in which a sample of bone tissue is taken and examined.
Management and Treatment
How is osteomalacia treated?
Patients who have osteomalacia can take vitamin D, calcium or phosphate supplements, depending on the individual case. For instance, people with intestinal malabsorption (the intestines cannot absorb nutrients or vitamins properly) may need to take larger quantities of vitamin D and calcium.
Other treatments to relieve or correct osteomalacia symptoms may include:
- Wearing braces to reduce or prevent bone irregularities
- Surgery to correct bone deformities (in severe cases)
- Adequate exposure to sunlight
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